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Patrick J Rochette Selected Research

Pyrimidine Dimers

12/2020Apple Extract (Malus sp.) and Rutin as Photochemopreventive Agents: Evaluation of Ultraviolet B-Induced Alterations on Skin Biopsies and Tissue-Engineered Skin.
1/2018Persistence and Tolerance of DNA Damage Induced by Chronic UVB Irradiation of the Human Genome.
1/2017Influence of a pre-stimulation with chronic low-dose UVB on stress response mechanisms in human skin fibroblasts.
4/2010Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair.
9/2005SW480, a p53 double-mutant cell line retains proficiency for some p53 functions.
8/2002Human cells bearing homozygous mutations in the DNA mismatch repair genes hMLH1 or hMSH2 are fully proficient in transcription-coupled nucleotide excision repair.

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Patrick J Rochette Research Topics

Disease

4Fuchs' Endothelial Dystrophy
01/2021 - 11/2016
2Macular Degeneration (Age-Related Maculopathy)
01/2021 - 03/2013
2Skin Neoplasms (Skin Cancer)
01/2018 - 04/2010
2Neoplasms (Cancer)
01/2017 - 01/2016
1Sunburn
12/2020
1Hypersensitivity (Allergy)
04/2010
1Lung Neoplasms (Lung Cancer)
02/2010
1Rothmund-Thomson Syndrome (Syndrome, Rothmund-Thomson)
10/2009
1Adenocarcinoma
09/2005
1Genomic Instability
08/2002
1Colonic Neoplasms (Colon Cancer)
08/2002

Drug/Important Bio-Agent (IBA)

6Pyrimidine DimersIBA
12/2020 - 08/2002
1Matrix Metalloproteinases (MMPs)IBA
01/2021
1Caspase 3 (Caspase-3)IBA
12/2020
1IntegrinsIBA
01/2018
1Proteins (Proteins, Gene)FDA Link
01/2018
1Biological ProductsIBA
01/2016
1Mitochondrial DNA (mtDNA)IBA
03/2013
1OligonucleotidesIBA
04/2010
17,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxideIBA
02/2010
1SmokeIBA
02/2010
1Benzo(a)pyreneIBA
02/2010
1RecQ HelicasesIBA
10/2009
1DNA AdductsIBA
08/2002
1DNA (Deoxyribonucleic Acid)IBA
08/2002

Therapy/Procedure

1Intraocular Lenses (Intraocular Lens)
01/2021
1Corneal Transplantation (Keratoplasty)
11/2016